About
About EXCELSE™ High Concentration Formulation Technology Some proteins are effective only at high doses requiring larger volumes or concentrated delivery, which creates inconvenience for patients, higher costs for payers and at times efficacy and safety challenges. The EXCELSE™ formulation technology uses customized blends of amino acids to highly stabilize and concentrate delicate biotechnology medicines. This is achieved by using proprietary blends of amino acids that coats key regions of the molecule, allowing them to be concentrated together without clumping or becoming unstable. In research studies, concentrations of up to 300 mg/ml have been reached enabling a switch to small subcutaneous doses. The EXCELSE technology can also turn powdered drugs into liquids, or allow field administration via room temperature storage conditions where drug refrigeration is difficult such as vaccines in the developing world.